AgedBrainSYSBIO

Portrait of Professor Simonneau, Scientific Coordinator of AgedBrainSYSBIO

Prof. Michel Simonneau

Scientific Coordinator of AgedBrainSYSBIO, based at Institut National de la Santé et de la Recherche Médicale (Inserm) in Paris, France

Research field

Healthy Ageing, Systems Biology, Alzheimer's

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Research Profile

Who?

“Research on the brain and ageing requires strong interactions between multidisciplinary researchers”, says Michel Simonneau. He is enthusiastic when he talks about AgedBrainSYSBIO. Professor Simonneau is a group leader at the Inserm Center for Psychiatry & Neuroscience in Paris and he teaches Neurobiology at ENS Cachan.

Why?

Neurodegenerative diseases and cognitive decline are great public health challenges of this time. Nearly 50% of adults over 85 suffer from neurodegenerative diseases such as Alzheimer’s. We have a broad understanding of the biological principles of human ageing, but we have no curative drugs for the associated diseases yet.

What?

AgedBrainSYSBIO researchers study brain ageing. Prof. Simonneau: “We investigate the pathways and interactions involved in brain ageing. We aim to find therapeutic targets and biomarkers for late-onset Alzheimer’s disease. Our scientists focus in particular on protein networks involved in the communication between nerve cells”.

How?

Prof. Simonneau: "This ambitious project integrates numerous European and national initiatives. We receive the input of four small to medium-sized enterprises allowing us to get solutions for curing and preventing common age-related diseases. The links between academia and industry is the driving force of this work programme”.

Understanding the biology of brain ageing

In the Picture
In the Picture
AgedBrainSYSBIO project website Alzheimer Europe Synsys (a related project) JPND (a related project) ALCOVE (a related project) Hello Brain: What can I do to keep my brain healthy? French National Institute of Health and Medical Research (Inserm) AgedBrainSYSBIO project leaflet In Focus article 'When the brain starts to shed its leaves' Video: how can I keep my brain sharp? Video: What makes your brain work? Brain Facts PDF versionPDF version
Image credits

Background image: Ben Cadet

Portrait of the project coordinator: AgedBrainSYSBIO

Timeline (in chronological order): 2009: J.C. Lambert and al ; other years: Wikimedia Commons