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REDDSTAR

Prof. Tim O' Brien

Scientific Coordinator of REDDSTAR and Director of the Regenerative Medicine Institute (REMEDI), based at the National University of Ireland, Galway

Research field

Health and Innovation, Diabetes

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If you want to know more

Who?

Tim O'Brien: “As an endocrinologist, I see patients with non-healing foot ulcers often resulting in amputation. Every 20 seconds someone in the world loses a foot due to a diabetic foot ulcer. This motivates me to develop new methods to treat diabetes. Stem cell research may lead to new insights and better patient outcomes.”

Why?

At least 180 million people worldwide suffer from diabetes. Many of them use prescription drugs to control blood glucose levels. Serious problems arise when these drugs do not work properly. This can cause damage to the heart, retina, nerve tissue and kidneys. It can also result in poor bone fracture repair and wound healing.

What?

Prof.O’Brien: “We will examine if bone marrow-derived stromal stem cells can safely control blood glucose levels in diabetes patients.” These cells are located in adult bone marrow. They are progenitors of bone, cartilage and fat cells. “We also want to find out if the cells can reduce damage caused by diabetic complications.”

How?

“We hope that stromal stem cells can reduce diabetic complications. No single country harbours the depth of expertise that we need to improve diabetes therapy”, says Prof. O’Brien. Therefore, REDDSTAR has assembled a team of scientists in Ireland, Northern Ireland, Portugal, Germany, the USA, Denmark and the Netherlands.